Reviews

We understand that the immunology research field is challenging to keep on top of. That’s why we created a series of three weekly immunology newsletters: Human Immunology News and Immunology of Infectious Disease in addition to Immune Regulation News. It’s also why we feature at least one recent, relevant review paper in each issue. We archive every review featured in Immune Regulation News here, providing a comprehensive list of review papers to help you catch up, and keep up, with your field. Did we miss a new review? You can submit a recent review and we will try to include it in the next issue of Immune Regulation News.
Title   Journal   Publication Date   Newsletter Issue  
Treg Cell-Based Therapies: Challenges and Perspectives Raffin, C; Vo, LT; Bluestone, JA Nat Rev Immunol 2019-12-06 11.46 | Dec 6
The Influence of Environment and Origin on Brain Resident Macrophages and Implications for Therapy Bennett, ML; Bennett, FC Nat Neurosci 2019-12-02 11.46 | Dec 6
Engineering Dendritic Cell Vaccines to Improve Cancer Immunotherapy Perez, CR; De Palma, M Nat Commun 2019-11-27 11.45 | Nov 29
Roles of Aminoacyl-tRNA Synthetases in Immune Regulation and Immune Diseases Nie, A; Sun, B; Fu, Z; Yu, D Cell Death Dis 2019-11-28 11.45 | Nov 29
TSLP: From Allergy to Cancer Corren, J; Ziegler, SF Nat Immunol 2019-11-19 11.44 | Nov 22
Controlling Immunity and Inflammation through Integrin-Dependent Regulation of TGF-β Nolte, M; Margadant, C Trends Cell Biol 2019-11-16 11.44 | Nov 22
B Cells in Autoimmune and Neurodegenerative Central Nervous System Diseases Sabatino Jr., JJ; Probstel, AK; Zamvil, SS Nat Rev Neurosci 2019-11-11 11.43 | Nov 15
Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors Grosser, R; Cherkassky, L; Chintala, N; Adusumilli, PS Cancer Cell 2019-11-11 11.43 | Nov 15
The Cytokine Network Involved in the Host Immune Response to Periodontitis Pan, W; Wang, Q; Chen, Q Int J Oral Sci 2019-11-05 11.42 | Nov 8
Emerging Activators and Regulators of Inflammasomes and Pyroptosis Xue, Y; Tuipulotu, DE; Tan, WH; Kay, C; Man, SM Trends Immunol 2019-10-26 11.41 | Nov 1
Epigenetic Regulation of Macrophages: From Homeostasis Maintenance to Host Defense Chen, S; Yang, J; Wei, Y; Wei, X Cell Mol Immunol 2019-10-29 11.41 | Nov 1
Immune Reconstitution Therapies: Concepts for Durable Remission in Multiple Sclerosis Lünemann, JD; Ruck, T; Muraro, PA; Bar’Or A; Wiendl, H Nat Rev Neurol 2019-10-24 11.40 | Oct 24
Developing Neoantigen-Targeted T Cell-Based Treatments for Solid Tumors Yamamoto, TN; Kishton, RJ; Restifo, NP Nat Med 2019-10-07 11.38 | Oct 11
Adaptive Immunity: An Emerging Player in the Progression of NAFLD Sutti, S; Albano, E Nat Rev Gastroenterol Hepatol 2019-10-11 11.38 | Oct 11
The Role of Innate Immunity in Asthma Development and Protection: Lessons from the Environment Pivniouk, V; Gimenes Junior JA; Honeker, L; Vercelli, D Clin Exp Allergy 2019-10-03 11.37 | Oct 4
The tRNA‐Associated Dysregulation in Immune Responses and Immune Diseases Zhu, C; Sun, B; Nie, A; Zhou, Z Acta Physiol 2019-09-17 11.36 | Sep 27
Next-Generation Regulatory T Cell Therapy Ferreira, LMR; Muller, YD; Bluestone, JA; Tang, Q Nat Rev Drug Discov 2019-09-20 11.35 | Sep 20
The Heterogeneous Pathogenesis of Type 1 Diabetes Mellitus Ilonen, J; Lempainen, J; Veijola, R Nat Rev Endocrinol 2019-09-18 11.35 | Sep 20
Targeting Innate Immune Mediators in Type 1 and Type 2 Diabetes Donath, MY; Dinarello, CA; Mandrup-Poulsen, T Nat Rev Immunol 2019-09-09 11.34 | Sep 13
The Multifaceted Immune Regulation of Bladder Cancer Schneider, AK; Chavalier, MF; Derre, L Nat Rev Urol 2019-09-09 11.34 | Sep 13
Translating Gammadelta (γδ) T Cells and Their Receptors into Cancer Cell Therapies Sebestyen, Z; Prinz, I; Dechenet-Merville, J; Silva-Santos, B; Kuball, J Nat Rev Drug Discov 2019-09-06 11.33 | Sep 6
Immune Regulation of Metabolic Homeostasis by Helminths and Their Molecules van der Zande, HJP; Zawistowska-Deniziak, A; Guigas, B Trends Parasitol 2019-09-03 11.33 | Sep 6
Dendritic Cells in Cancer Immunology and Immunotherapy Wculek, SK; Cueot, FJ; Mujal, AM; Melero, I; Krummel, MF; Sancho, D Nat Rev Immunol 2019-08-29 11.32 | Aug 30
Zebrafish in Inflammasome Research Forn-Cuni, G; Meijer, AH; Varela, M Cells 2019-08-15 11.31 | Aug 23
Metabolic Coordination of T Cell Quiescence and Activation Chapman, NM; Boothby, MR; Chi, H Nat Rev Immunol 2019-08-12 11.30 | Aug 16
Engineering Universal Cells That Evade Immune Detection Godfrey, DI; Koay, HF; McCluskey, J; Gherardin, NA Nat Rev Immunol 2019-08-15 11.30 | Aug 16
ILC Regulation of T Cell Responses in Inflammatory Diseases and Cancer Warner, K; Ohashi, PS Semin Immunol 2019-08-02 11.29 | Aug 9
Targeting Metabolism to Regulate Immune Responses in Autoimmunity and Cancer Patel, CH; Leone, RD; Horton, MR; Powell, JD Nat Rev Drug Discov 2019-07-30 11.28 | Aug 2
Macrophages at CNS Interfaces: Ontogeny and Function in Health and Disease Kierdorf, K; Masuda, T; Jordao, MJC; Prinz, M Nat Rev Neurosci 2019-07-29 11.28 | Aug 2
Functional Interactions between Innate Lymphoid Cells and Adaptive Immunity Sonnenberg, GF; Hepworth, MR Nat Rev Immunol 2019-07-26 11.27 | Jul 26
Pas de Deux: Control of Anti-Tumor Immunity by Cancer-Associated Inflammation Shalapour, S; Karin, M Immunity 2019-07-16 11.26 | Jul 16
Inflammation and Cancer: Triggers, Mechanisms, and Consequences Greten, FR; Grivennikov, SI Immunity 2019-07-16 11.26 | Jul 16
T Follicular Helper Cells and T Follicular Regulatory Cells in Rheumatic Diseases Deng, J; Wei, Y; Fonseca, VR; Graca, L; Yu, D Nat Rev Rheumatol 2019-07-09 11.25 | Jul 12
Staphylococcus epidermidis Role in the Skin Microenvironment Leonel, C; Sena, IFG; Silva, WN; Prazeres, PHDM; Fernandes, GR; Agresti, PM; Drumond, MM; Mintz, A; Azevedo, VAC; Birbrair, A J Cell Mol Med 2019-07-06 11.25 | Jul 12
Targeting Immune Cell Circuits and Trafficking in Inflammatory Bowel Disease Neurath, MF Nat Immunol 2019-06-24 11.24 | Jul 5
Microbial Genes and Pathways in Inflammatory Bowel Disease Schirmer, M; Garner, A; Vlamakis, H; Xavier, RJ Nat Rev Microbiol 2019-06-27 11.23 | Jun 28
Tissue-Resident Memory T Cells in Cancer Immunosurveillance Park, SL; Gebhardt, T; Mackay, LK Trends Immunol 2019-06-26 11.23 | Jun 28
γδ T Cells: Pleiotropic Immune Effectors with Therapeutic Potential in Cancer Silva-Santos, B; Mensurado, S; Coffelt, SB Nat Rev Cancer 2019-06-21 11.22 | Jun 21
Adaptation and Memory in Immune Responses Natoli, G; Ostuni, R Nat Immunol 2019-06-18 11.22 | Jun 21
Metabolic Adaptations of Tissue-Resident Immune Cells Caputa, G; Castoldi, A; Pearce, EJ Nat Immunol 2019-06-18 11.22 | Jun 21
Systemic Effects of IL-17 in Inflammatory Arthritis Beringer, A; Miossec, P Nat Rev Rheumatol 2019-06-21 11.22 | Jun 21
Interferon-λ Orchestrates Innate and Adaptive Mucosal Immune Responses Ye, L; Schnepf, D; Staeheli, P Nat Rev Immunol 2019-06-14 11.21 | Jun 14
The Potential of Astrocytes as Immune Modulators in Brain Tumors Priego, N; Valiente, M Front Immunol 2019-06-11 11.21 | Jun 14
Regulation of Innate Immune Responses by Platelets Ribeiro, LS; Branco, LM; Franklin, BS Front Immunol 2019-06-11 11.21 | Jun 14
Tumor-Associated Neutrophils in Patients with Cancer Shaul, ME; Fridlender, ZG Nat Rev Clin Oncol 2019-06-03 11.20 | Jun 7
The Microbiome and Immune Memory Formation McCoy, KD; Burkhard, R; Geuking, MB Immunol Cell Biol 2019-05-25 11.19 | May 31
Regulation of Immune Responses by Tuft Cells Schneider, C; O’Leary, CE; Locksley, RM Nat Rev Immunol 2019-05-21 11.18 | May 24
The Role of Macrophages in the Resolution of Inflammation Watanabe, S; Alexander, M; Misharin, AV; Budinger, GRS J Clin Invest 2019-05-20 11.18 | May 24
Adverse Effects of Immune-Checkpoint Inhibitors: Epidemiology, Management and Surveillance Martins, F; Sofiya, L; et al Nat Rev Clin Oncol 2019-05-15 11.17 | May 17
Regulatory Immune Mechanisms beyond Regulatory T Cells Christoffersson, G; von Herrath, M Trends Immunol 2019-05-14 11.17 | May 17
Competition for Nutrients and Its Role in Controlling Immune Responses Kedia-Mehta, N; Finlay, DK Nat Commun 2019-05-04 11.16 | May 10
The Presentation of Neuroendocrine Self‐Peptides in the Thymus: An Essential Event for Individual Life and Vertebrate Survival Geenen, V; Trussart, C; et al Ann N Y Acad Sci 2019-04-22 11.16 | May 10
New Insights into the Immune Functions of Complement Reis, ES; Mastellos, DC; Hajishengallis, G; Lambris, JD Nat Rev Immunol 2019-05-02 11.15 | May 3
T Cells and the Skin: From Protective Immunity to Inflammatory Skin Disorders Ho, AW; Kupper, TS Nat Rev Immunol 2019-04-16 11.14 | Apr 26
B Cell Checkpoints in Autoimmune Rheumatic Diseases Rubin, SJS; Bloom, MS; Robinson, WH Nat Rev Rheumatol 2019-04-09 11.13 | Apr 12
ILC3 Function as a Double-Edged Sword in Inflammatory Bowel Diseases Zeng, B; Shi, S; Ashworth, G; Dong, C; Liu, J; Xing, F Cell Death Dis 2019-04-08 11.13 | Apr 12
Harnessing the Innate Immune System and Local Immunological Microenvironment to Treat Colorectal Cancer Kather, JN; Halama, N Br J Cancer 2019-04-02 11.12 | Apr 5
Navigating Metabolic Pathways to Enhance Antitumor Immunity and Immunotherapy Li, X; Wenes, M; Romero, P; Huang, SCC; Fendt, SM; Ho, PC Nat Rev Clin Oncol 2019-03-26 11.11 | Mar 29
NK Cell Recognition of Hematopoietic Cells by SLAM-SAP Families Chen, S; Dong, Z Cell Mol Immunol 2019-03-25 11.11 | Mar 29
Targeting Natural Killer Cells in Solid Tumors Habif, G; Crinier, A; Andre, P; Vivier, E; Nani-Mancinelli, E Cell Mol Immunol 2019-03-25 11.11 | Mar 29
Regulatory T Cell Adaptation in the Intestine and Skin Whibley, N; Tucci, A; Powrie, F Nat Immunol 2019-03-19 11.10 | Mar 22
Targeting Tumor-Associated Macrophages in Cancer Pathria, P; Louis, TL; Varner, JA Trends Immunol 2019-03-16 11.10 | Mar 22
Innate, Innate-Like and Adaptive Lymphocytes in the Pathogenesis of MS and EAE Kaer, LV; Postoak, JL; Wang, C; Yang, G; Wu, L Cell Mol Immunol 2019-03-15 11.09 | Mar 15
Regulatory Cytokine Function in the Respiratory Tract Branchett, WJ; Lloyd, CM Mucosal Immunol 2019-03-15 11.09 | Mar 15
The Evolving Role of T-Bet in Resistance to Infection Pritchard, GH; Kedl, RM; Hunter, CA Nat Rev Immunol 2019-03-07 11.08 | Mar 8
Sensing of Physiological Regulators by Innate Lymphoid Cells Seillet, C; Jacquelot, N Cell Mol Immunol 2019-03-06 11.08 | Mar 8
Immunometabolism and Natural Killer Cell Responses O’Brien, K; Finlay, DK Nat Rev Immunol 2019-02-26 11.07 | Mar 1
Antigen-Specific Therapeutic Approaches for Autoimmunity Serra, P; Santamaria, P Nat Biotechnol 2019-02-25 11.07 | Mar 1
Immune Mechanisms of Salt-Sensitive Hypertension and Renal End-Organ Damage Mattson, DL Nat Rev Nephrol 2019-02-25 11.07 | Mar 1
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer Wing, JB; Tanaka, A; Sakaguchi, S Immunity 2019-02-19 11.06 | Feb 22
Orchestration between ILC2s and Th2 Cells in Shaping Type 2 Immune Responses Gurram, RK; Zhu, J Cell Mol Immunol 2019-02-21 11.06 | Feb 22
The Evolving Landscape of Biomarkers for Checkpoint Inhibitor Immunotherapy Havel, JJ; Chowell, D; Chan, TA Nat Rev Cancer 2019-02-12 11.05 | Feb 15
Macrophages as Regulators of Tumor Immunity and Immunotherapy DeNardo, DG; Ruffell, B Nat Rev Immunol 2019-02-04 11.04 | Feb 8
Regulation of the Innate Immune System by Autophagy: Monocytes, Macrophages, Dendritic Cells and Antigen Presentation Germic, N; Frangez, Z; Youdefi, S; Simon, HU Cell Death Differ 2019-02-08 11.04 | Feb 8
Regulation of the Innate Immune System by Autophagy: Neutrophils, Eosinophils, Mast Cells, NK Cells Germic, N; Frangez, Z; Youdefi, S; Simon, HU Cell Death Differ 2019-02-08 11.04 | Feb 8
Regulatory T Cells in Cancer Immunosuppression — Implications for Anticancer Therapy Togashi, Y; Shitara, K; Nishikawa, H Nat Rev Clin Oncol 2019-01-31 11.03 | Feb 1
Immunometabolism at the Interface between Macrophages and Pathogens Russell, DG; Huang, L; VanderVen, BC Nat Rev Immunol 2019-01-24 11.02 | Jan 25
Sodium in the Microenvironment Regulates Immune Responses and Tissue Homeostasis Muller, DN; Wilck, N; Haase, S; Kleinewietfeld, M; Linker, RA Nat Rev Immunol 2019-01-15 11.01 | Jan 18
The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy Souza-Fonseca-Guimaraes, F; Cursons, J; Huntington, ND Trends Immunol 2019-01-10 11.01 | Jan 18
From Therapeutic Antibodies to Immune Complex Vaccines Wang, XY; Wang, B; Wen, YM npj Vaccines 2019-01-17 11.01 | Jan 18
Developing Role of B Cells in the Pathogenesis and Treatment of Chronic GvHD Li, X; Gao, Q; Feng, Y; Zhang, X Br J Haematol 2019-12-26 11.00 | Jan 11
Cutaneous Immune Responses Mediated by Dendritic Cells and Mast Cells Sumpter, TL; Balmert, SC; Kaplan, DH JCI Insight 2019-01-10 11.00 | Jan 11
The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases Roncarolo, MG; Gregori, S; Bacchetta, R; Battaglia, M; Gagliani, N Immunity 2018-12-18 10.49 | Dec 21
Cancer Immunoediting and Resistance to T Cell-Based Immunotherapy O’Donnell, JS; Teng, MWL; Smyth, MJ Nat Rev Clin Oncol 2018-12-06 10.48 | Dec 14
Immune Checkpoint Inhibitors: Recent Progress and Potential Biomarkers Darvin, P; Toor, SM; Nair, VS; Elkord, E Exp Mol Med 2018-12-13 10.48 | Dec 14
Autophagy in the Renewal, Differentiation and Homeostasis of Immune Cells Clarke, AJ; Simon, AK Nat Rev Immunol 2018-12-07 10.47 | Dec 7
Organ-Specific Mechanisms of Transendothelial Neutrophil Migration in the Lung, Liver, Kidney, and Aorta Maas, SL; Soehnlein, O; Viola, JR Front Immunol 2018-11-27 10.47 | Dec 7
IL-6 and the Dysregulation of Immune, Bone, Muscle, and Metabolic Homeostasis during Spaceflight Smith, JK npj Microgravity 2018-12-04 10.47 | Dec 7
The Role of Macrophages in Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Kazankov, K; Jorgensen, SMD; Thomsen, KL; Moller, HJ; Vilstrup, H; George, J; Schuppan, D; Gronbaek, H Nat Rev Gastroenterol Hepatol 2018-11-27 10.46 | Nov 30
Regulatory T Cell Plasticity and Stability and Autoimmune Diseases Qiu, R; Zhou, L; Ma, Y; Zhou, L; Liang, T; Shi, L; Long, J; Yuan, D Clin Rev Allergy Immunol 2018-11-17 10.46 | Nov 30
Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules Maizels, RM; Smits, HH; McSorley, HJ Immunity 2018-11-20 10.45 | Nov 23
Innate-Like B Cell Subsets during Immune Responses: Beyond Antibody Production Romero-Ramírez, S; Navarro-Hernandez, IC; et al J Leukoc Biol 2018-11-20 10.45 | Nov 23
Effector and Regulatory B Cells in Immune-Mediated Kidney Disease Oleinika, K; Mauri, C; Salama, AD Nat Rev Nephrol 2018-11-15 10.44 | Nov 16
Non-Hematopoietic Control of Peripheral Tissue T Cell Responses: Implications for Solid Tumors Lane, RS; Lund, AW Front Immunol 2018-11-15 10.44 | Nov 16
Hypoxia-Inducible Factor-1α Regulation of Myeloid Cells Stothers, CL; Luan, L; Fensterheim, BA; Bohannon, JK J Mol Med 2018-11-01 10.43 | Nov 9
Two to Tango: Dialog between Immunity and Stem Cells in Health and Disease Naik, S; Larsen, SB; Cowley, CJ; Fuchs, E Cell 2018-11-01 10.42 | Nov 2
Anti-Inflammatory and Immune-Regulatory Cytokines in Rheumatoid Arthritis Chen, Z; Bozec, A; Ramming, A; Schett, G Nat Rev Rheumatol 2018-10-19 10.41 | Oct 26
From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology Al Bakir, I; Curtius, K; Graham, TA Front Immunol 2018-10-16 10.40 | Oct 19
Comparing the Effects of Different Cell Death Programs in Tumor Progression and Immunotherapy Messmer, MN; Snyder, AG; Oberst, A Cell Death Differ 2018-10-19 10.40 | Oct 19
Regulatory T Cells in the Treatment of Disease Sharabi, A; Tsokos, MG; Ding, Y; Malek, TR; Klatzmann, D; Tsokos, GC Nat Rev Drug Discov 2018-10-12 10.39 | Oct 12
Regulatory T Cells in Embryo Implantation and the Immune Response to Pregnancy Robertson, SA; Care, AS; Moldenhauer, LM J Clin Invest 2018-10-01 10.39 | Oct 12
T Helper Cell Differentiation, Heterogeneity, and Plasticity Zhu, J Cold Spring Harb Perspect Biol 2018-10-01 10.38 | Oct 5
Recent Advances on the Crosstalk between Neutrophils and B or T Lymphocytes Costa, S; Bevolacqua, D; Cassatella, MA; Scapini, P Immunology 2018-09-27 10.37 | Sep 28
Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development Yockey, LJ; Iwasaki, A Immunity 2018-09-18 10.36 | Sep 21
Cross-Talk between Lung Cancer and Bones Results in Neutrophils that Promote Tumor Progression Azevedo, PO; Paiva, AE; Santos, GSP; Lousado, L; Andreotti, JP; Sena, IF; Tagliati, CA; Mintz, A; Birbrair, A Cancer Metastasis Rev 2018-09-10 10.35 | Sep 14
Recording the Wild Lives of Immune Cells Pittet, MJ; Garris, CS; Arlauckas, SP; Weissleder, R Sci Immunol 2018-09-07 10.35 | Sep 14
Forkhead Box Transcription Factors as Context-Dependent Regulators of Lymphocyte Homeostasis Zaiss, D; Coffer, P Nat Rev Immunol 2018-09-03 10.34 | Sep 7
Nutritional Modulation of Innate Immunity: The Fat–Bile–Gut Connection Chevre, R; Silvestre-Roig, C; Soehnlein, O Trends Endocrinol Metab 2018-09-06 10.34 | Sep 7
Immunomodulation of Tumor Vessels: It Takes Two to Tango Johansson-Percival, A; He, B; Ganss, R Trends Immunol 2018-08-25 10.33 | Aug 31
Biomaterial-Assisted Targeted Modulation of Immune Cells in Cancer Treatment Wang, H; Mooney, DJ Nat Mater 2018-08-13 10.32 | Aug 24
From Stability to Dynamics: Understanding Molecular Mechanisms of Regulatory T Cells through Foxp3 Transcriptional Dynamics Bending, D; Ono, M Clin Exp Immunol 2018-08-04 10.31 | Aug 17
Regulation of T Cell Immunity by Cellular Metabolism Hu, Z; Zou, Q; Su, B Front Med 2018-08-16 10.31 | Aug 17
Neuro-Immune Regulation of Mucosal Physiology Chesne, J; Cardoso, V; Veiga-Fernandes, H Mucosal Immunol 2018-08-08 10.30 | Aug 10
CD4+ T Cell Help in Cancer Immunology and Immunotherapy Borst, J; Ahrends, T; Babala, N; Melief, CJM; Kastenmuller, W Nat Rev Immunol 2018-07-29 10.29 | Aug 3
Histone Deacetylase Function in CD4+ T Cells Ellmeier, W; Seiser, C Nat Rev Immunol 2018-07-18 10.28 | Jul 27
Regulation of Neutrophils in Type 2 Immune Responses Heeb, LEM; Egholm, C; Impellizzieri, D; Ridder, D; Boyman, O Curr Opin Immunol 2018-07-13 10.27 | Jul 20
Delivery Strategies for Immune Checkpoint Blockade Chen, Q; Wang, C; Chen, G; Hu, Q; Gu, Z Adv Healthc Mater 2018-07-05 10.26 | Jul 13
Tissue-Specific Functions of Invariant Natural Killer T Cells Crosby, CM; Kronenberg, M Nat Rev Immunol 2018-07-02 10.25 | Jul 6
MicroRNA miR-223 as Regulator of Innate Immunity Yuan, X; Berg, N; Lee, JW; Le, TT; Neudecker, V; Jing, N; Eltzschig, H J Leukoc Biol 2018-07-03 10.25 | Jul 6
Promises and Limitations of Immune Cell-Based Therapies in Neurological Disorders Hu, X; Leak, RK; Thomson, AW; Yu, F; Xia, Y; Wechsler, LR; Chen, J Nat Rev Neurol 2018-06-20 10.24 | Jun 29
Regulatory T Cells in Autoimmune Disease Dominguez-Villar, M; Hafler, DA Nat Immunol 2018-06-20 10.23 | Jun 22
TGF-β in T Cell Biology: Implications for Cancer Immunotherapy Dahmani, A; Delisle, JS Genes (Basel) 2018-06-11 10.22 | Jun 15
Antigen-Specific Regulatory T-Cell Responses against Aeroantigens and Their Role in Allergy Bacher, P; Scheffold, A Mucosal Immunol 2018-06-01 10.22 | Jun 7
Antigen-Specific Regulatory T-Cell Responses against Aeroantigens and Their Role in Allergy Bacher, P; Scheffold, A Mucosal Immunol 2018-06-01 10.20 | Jun 1
Defining and Understanding Adaptive Resistance in Cancer Immunotherapy Kim, TK; Herbst, RS; Chen, L Trends Immunol 2018-05-22 10.20 | May 25
Regulation of Macrophage Immunometabolism in Atherosclerosis Koelwyn, GJ; Corr, EM; Erbay, E; Moore, KJ Nat Immunol 2018-05-18 10.18 | May 18
Metabolism as a Target for Modulation in Autoimmune Diseases Huang, N; Peri, A Trends Immunol 2018-05-05 10.17 | May 11
The Pathogenicity of IL-33 on Steroid-Resistant Eosinophilic Inflammation via the Activation of Memory-Type ST2+CD4+ T Cells Hirahara, K; Mato, N; Hagiwara, K; Nakayama, T J Leukoc Biol 2018-04-30 10.16 | May 4
The Opposing Roles of CD4+ T Cells in Anti-Tumor Immunity Ahrends, T; Borst, J Immunology 2018-04-27 10.16 | May 4
Control of T Cell Effector Functions by miRNAs Inacio, DP; Amado, T; Silva-Santos, B; Gomes, AQ Cancer Lett 2018-04-18 10.15 | Apr 27
Clocking in to Immunity Scheiermann, C; Gibbs, J; Ince, L; Loudon, A Nat Rev Immunol 2018-04-16 10.14 | Apr 20
Beyond Host Defense: Emerging Functions of the Immune System in Regulating Complex Tissue Physiology Rankin, LC; Artis, D Cell 2018-04-19 10.14 | Apr 20
The Role of Extracellular Vesicles When Innate Meets Adaptive Groot Kormelink, T; Mol, S; de Jong, EC; Wauben, MHM Semin Immunopathol 2018-04-03 10.13 | Apr 13
Autophagy in Dendritic Cells Ghislat, G; Lawrence, T Cell Mol Immunol 2018-03-26 10.12 | Apr 6
When Worlds Collide: Th17 and Treg Cells in Cancer and Autoimmunity Knochelmann, HM; Dwyer, CJ; Bailey, SR; Amaya, SM; Elston, DM; Mazza-McCrann, JM; Paulos, CM Cell Mol Immunol 2018-03-21 10.11 | Mar 23
Unmasking Fucosylation: From Cell Adhesion to Immune System Regulation and Diseases Li, J; Hsu, HC; Mountz, JD; Allen, JG Cell Chem Biol 2018-03-08 10.10 | Mar 16
Transcriptional Regulation and Development of Regulatory T Cells Lee, W; Lee, GR Exp Mol Med 2018-03-09 10.09 | Mar 9
Lipid Droplets as Immune Modulators in Myeloid Cells den Brok, MH; Raaijmakers, TK; Collado-Camps, E; Adema, GJ Trends Immunol 2018-02-22 10.08 | Mar 2
Delicate Regulation of the cGAS–MITA-Mediated Innate Immune Response Luo, WW; Shu, HB Cell Mol Immunol 2018-02-18 10.07 | Feb 23
Regulation of T Cell Signaling by Membrane Lipids Wu, W; Shi, X; Xu, C Nat Rev Immunol 2018-02-12 10.06 | Feb 16
Functions of NKG2D in CD8+ T Cells: An Opportunity for Immunotherapy Prajapati, K; Perez, C; Rojas, LBP; Burke, B; Guevara-Patino, JA Cell Mol Immunol 2018-02-09 10.05 | Feb 9
Epigenetic Regulation in B-Cell Maturation and Its Dysregulation in Autoimmunity Wu, H; Deng, Y; Feng, Y; Long, D; Ma, K; Wang, X; Zhao, M; Lu, L; Lu, Q Cell Mol Immunol 2018-01-29 10.04 | Feb 2
Epigenetic Control of CD8+ T Cell Differentiation Henning, AN; Roychoudhuri, R; Restifo, NP Nat Rev Immunol 2018-01-30 10.04 | Feb 2
Epigenetics, Microbiota, and Intraocular Inflammation: New Paradigms of Immune Regulation in the Eye Wen, X; Hu, X; Miao, L; Ge, X; Deng, Y; Bible, PW; Wei, L Prog Retin Eye Res 2018-01-19 10.03 | Jan 26
Bacterial Pathogenesis and Interleukin-17: Interconnecting Mechanisms of Immune Regulation, Host Genetics, and Microbial Virulence that Influence Severity of Infection Chamoun, MN; Blumenthal, A; Sullivan, MJ; Schembri, MA; Ulett, GC Crit Rev Microbiol 2018-01-18 10.03 | Jan 26
Regulation of the Immune Response by the Aryl Hydrocarbon Receptor Gutiérrez-Vázquez, C; Quintana, FJ Immunity 2018-01-16 10.02 | Jan 19
Myeloid-Derived Suppressor Cells Coming of Age Veglia, F; Perego, M; Gabrilovich, D Nat Immunol 2018-01-18 10.02 | Jan 19
Immunomodulatory Nonstructural Proteins of Influenza A Viruses Klemm, C; Boergeling, Y; Ludwig, S; Ehrhardt, C Trends Microbiol 2018-01-17 10.02 | Jan 19
Updating Osteoimmunology: Regulation of Bone Cells by Innate and Adaptive Immunity Walsh, MC; Takegahara, N; Kim, H; Choi, Y Nat Rev Rheumatol 2018-01-11 10.01 | Jan 12
Regulatory T Cells as a New Therapeutic Target for Atherosclerosis Ou, H-X; Guo, B-B; Liu, Q; Li, Y-K; Yang, Z; Feng, W-J; Mo, Z-C Acta Pharmacol Sin 2018-01-11 10.01 | Jan 12
Autoimmunity and Primary Immunodeficiency: Two Sides of the Same Coin? Schmidt, RE; Grimbacher, B; Witte, T Nat Rev Rheumatol 2017-12-19 10.00 | Jan 5
Metabolic Control of CD8+ T Cell Fate Decisions and Antitumor Immunity Zhang, L; Romero, P Trends Mol Med 2017-12-12 9.48 | Dec 15
Noncoding RNAs: Master Regulators of Inflammatory Signaling Chew, CL; Conos, SA; Unal, B; Tergaonkar, V Trends Mol Med 2017-12-12 9.48 | Dec 15
The Role of Semaphorins in Immune Responses and Autoimmune Rheumatic Diseases Nishide, M; Kumanogoh, A Nat Rev Rheumatol 2017-12-07 9.47 | Dec 8
ZBP1: Innate Sensor Regulating Cell Death and Inflammation Kuriakose, T; Kanneganti, T-D Trends Immunol 2017-11-24 9.46 | Dec 1
Mast Cells as Drivers of Disease and Therapeutic Targets Siebenhaar, F; Redegeld, FA; Bischoff, SC; Gibbs, BF; Maurer, M Trends Immunol 2017-11-28 9.46 | Dec 1
Nerve Stimulation: Immunomodulation and Control of Inflammation Ulloa, L; Quiroz-Gonzalez, S; Torres-Rosas, R Trends Mol Med 2017-11-20 9.45 | Nov 24
Immune Checkpoint Inhibitors in Sarcomas: In Quest of Predictive Biomarkers Veenstra, R; Kostine, M; Cleton-Jansen, AM; de Miranda, NF; Bovée, JV Lab Invest 2017-11-20 9.45 | Nov 24
Harnessing the Power of Regulatory T Cells to Control Autoimmune Diabetes: Overview and Perspective Yu, H; Paiva, R; Flavell, RA Immunology 2017-11-20 9.45 | Nov 24
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Review Series on Immune Responses in Neurodegenerative Diseases: Innate and Adaptive Immune Responses in Neurodegeneration and Repair Amor, S; Woodroofe, N Immunology 2013-06-12 5.23 | Jun 21
On Guard: Coronin Proteins in Innate and Adaptive Immunity Pieters, J; Müller, P; Jayachandran, R Nat Rev Immunol 2013-06-14 5.22 | Jun 14
The Relationship between Metabolism and the Autophagy Machinery during the Innate Immune Response Martinez, J; Verbist, K; Wang, R; Green, DR Cell Metab 2013-06-04 5.22 | Jun 14
T Cell Regulation of Natural Killer Cells Kerdiles, Y; Ugolini, S; Vivier, E J Exp Med 2013-06-03 5.21 | Jun 7
Activation and Regulation of the Inflammasomes Latz, E; Xiao, TS; Stutz, A Nat Rev Immunol 2013-05-24 5.20 | May 31
Friendly Pathogens: Prevent or Provoke Autoimmunity Sathyabama, S; Khan, N; Agrewala, JN Crit Rev Microbiol 2013-05-21 5.20 | May 31
B-Regulatory Cells in Autoimmunity and Immune Mediated Inflammation Vadasz, Z; Haj, T; Kessel, A; Toubi, E FEBS Lett 2013-05-22 5.20 | May 31
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Regulation of Innate and Adaptive Immunity by Notch Radtke, F; MacDonald, HR; Tacchini-Cottier, F Nat Rev Immunol 2013-05-13 5.18 | May 17
The Innate Immune Response during Liver Inflammation and Metabolic Disease Bieghs, V; Trautwein, C Trends Immunol 2013-05-11 5.18 | May 17
Cell-Based Immunotherapy against Gliomas: From Bench to Bedside Bovenberg, MS; Degeling, MH; Tannous, BA Mol Ther 2013-05-07 5.17 | May 10
Beyond Oxidative Stress: An Immunologist’s Guide to Reactive Oxygen Species Nathan, C; Cunningham-Bussel, A Nat Rev Immunol 2013-05-01 5.16 | May 3
The Th17 Pathway as a Therapeutic Target in Rheumatoid Arthritis and Other Autoimmune and Inflammatory Disorders Roeleveld, DM; van Nieuwenhuijze, AE; van den Berg, WB; Koenders, MI BioDrugs 2013-10-01 5.16 | May 3
Macrophage Biology in Development; Homeostasis and Disease Wynn, TA; Chawla, A; Pollard, JW Nature 2013-04-25 5.15 | Apr 26
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The Integration of T Cell Migration; Differentiation and Function Masopust, D; Schenkel, JM Nat Rev Immunol 2013-04-19 5.14 | Apr 19
Molecular Mechanisms of Natural Killer Cell Activation in Response to Cellular Stress Chan, CJ; Smyth, MJ; Martinet, L Cell Death Differ 2013-04-12 5.14 | Apr 19
Importance of Reverse Signaling of the TNF Superfamily in Immune Regulation Juhász, K; Buzás, K; Duda, E Expert Rev Clin Immunol 2013-04-01 5.13 | Apr 12
Modulating T Regulatory Cells in Cancer: How Close Are We? Banerjee, A; Vasanthakumar, A; Grigoriadis, G Immunol Cell Biol 2013-04-09 5.13 | Apr 12
Interaction between Natural Killer Cells and Regulatory T Cells: Perspectives for Immunotherapy Pedroza-Pacheco, I; Madrigal, A; Saudemont, A Cel Mol Immunol 2013-03-25 5.12 | Apr 5
T Cell Receptor Signaling Networks: Branched; Diversified and Bounded Brownlie, RJ; Zamoyska, R Nat Rev Immunol 2013-04-01 5.12 | Apr 5
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting Merad, M; Sathe, P; Helft, J; Miller, J; Mortha, A Annu Rev Immunol 2013-03-01 5.12 | Apr 5
Molecular Mechanisms of T Cell Co-Stimulation and Co-Inhibition Chen, L; Flies, DB Nat Rev Immunol 2013-03-08 5.11 | Mar 22
Natural Killer Cells: Walking Three Paths Down Memory Lane Min-Oo, G; Kamimura, Y; Hendricks, DW; Nabekura, T; Lanier, LL Trends Immunol 2013-03-14 5.10 | Mar 15
Neutrophils Usher Monocytes Into Sites of Inflammation Swirski, FK; Robbins, CS Circ Res 2013-03-01 5.09 | Mar 8
Neutrophil Recruitment and Function in Health and Inflammation Kolaczkowska, E; Kubes, P Nat Rev Immunol 2013-03-01 5.08 | Mar 1
Regulation of Nuclear Factor-κB in Autoimmunity Sun, SC; Chang, JH; Jin, J Trends Immunol 2013-02-20 5.08 | Mar 1
Transcriptional Regulation of Follicular T-Helper (Tfh) Cells Liu, X; Nurieva, RI; Dong, C Immunol Rev 2013-02-13 5.07 | Feb 22
The Life of Regulatory T Cells Gratz, IK; Rosenblum, MD; Abbas, AK Ann NY Acad Sci 2013-02-12 5.07 | Feb 22
Negative Regulatory Approaches to the Attenuation of Toll-Like Receptor Signaling Anwar, MA; Basith, S; Choi, S Exp Mol Med 2013-02-22 5.07 | Feb 22
Intravenous Immunoglobulin Therapy: How Does IgG Modulate the Immune System? Schwab, I; Nimmerjahn, F Nat Rev Immunol 2013-02-15 5.06 | Feb 15
Activating Natural Cytotoxicity Receptors of Natural Killer Cells in Cancer and Infection Koch, J; Steinle, A; Watzl, C; Mandelboim, O Trends Immnunol 2013-02-13 5.06 | Feb 15
Regulatory Functions of Innate-Like B Cells Zhang, X Cell Mol Immunol 2013-02-11 5.06 | Feb 15
Circadian Control of the Immune System Scheiermann, C; Kunisaki, Y; Frenette, PS Nat Rev Immunol 2013-02-08 5.05 | Feb 8
Dendritic Cells and the Promise of Antigen-Specific Therapy in Rheumatoid Arthritis Thomas, R Arthritis Res Ther 2013-02-04 5.05 | Feb 8
Imaging Natural Killer T Cells in Action Wong, CH; Kubes, P Immunol Cell Biol 2013-02-05 5.05 | Feb 8
Six-of-the-Best: Unique Contributions of γδ T Cells to Immunology Vantourout, P; Hayday, A Nat Rev Immunol 2013-02-01 5.04 | Feb 1
Advances in Targeting Cell Surface Signaling Molecules for Immune Modulation Yao, S; Zhu, Y; Chen, L Nat Rev Drug Discov 2013-02-01 5.04 | Feb 1
Negative Regulation of Human Mononuclear Phagocyte Function Hedl, M; Abraham, C Mucosal Immunol 2013-01-23 5.04 | Feb 1
Invariant Natural Killer T Cells: An Innate Activation Scheme Linked to Diverse Effector Functions Brennan, PJ; Brigl, M; Brenner, MB Nat Rev Immunol 2013-01-21 5.03 | Jan 25
Innate B Cell Helpers Reveal Novel Types of Antibody Responses Vinuesa, CG; Chang, PP Nat Immunol 2013-01-18 5.02 | Jan 18
Regulatory B Cells in Autoimmune Diseases Yang, M; Rui, K; Wang, S; Lu, L Cell Mol Immunol 2013-01-07 5.02 | Jan 18
Metabolic Regulation of T Lymphocytes MacIver, NJ; Michalek, RD; Rathmell, JC Annu Rev Immunol 2013-01-03 5.01 | Jan 11
IL-27 in Tumor Immunity and Immunotherapy Murugaiyan, G; Saha, B Trends Mol Med 2013-01-07 5.01 | Jan 11
Therapeutic Opportunities for Manipulating TRegIntestinal Dendritic Cells in Migrational Imprinting of Immune cells Stock, A; Napolitani, G; Cerundolo, V Immunol Cell Biol 2013-01-08 5.01 | Jan 11
Therapeutic Opportunities for Manipulating TReg Cells in Autoimmunity and Cancer von Boehmer, H; Daniel, C Nat Rev Drug Discov 2013-01-01 5.00 | Jan 4
Inflammatory Monocytes and the Pathogenesis of Viral Encephalitis Terry, RL; Getts, DR; Deffrasnes, C; van Vreden, C; Campbell, IL; King, NJ J Neuroinflamm 2012-12-17 4.49 | Dec 21
The Where and When of T Cell Regulation in Transplantation Issa, F; Robb, RJ; Wood, KJ Trends Immunol 2012-12-07 4.48 | Dec 14
Immunoregulation through Membrane Proteins Modified by Reducing Conditions Induced by Immune Reactions Stegmann, M; Metcalfe, C; Barclay, AN Eur J Immunol 2012-12-11 4.48 | Dec 14
Differentiation and Function of Foxp3+ Effector Regulatory T Cells Cretney, E; Kallies, A; Nutt, SL Trends Immunol 2012-12-06 4.47 | Dec 7
B Regulatory Cells in Cancer Balkwill, F; Montfort, A; Capasso, M Trends Immunol 2012-12-01 4.47 | Dec 7
Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells: What Have We Learned so Far? Griffin, MD; Ryan, AE; Alagesan, S; Lohan, P; Treacy, O; Ritter, T Immunol Cell Biol 2012-12-04 4.47 | Dec 7
Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis: Where Are We Now? Hilkens, CM; Isaacs, JD Clin Exp Immunol 2012-11-23 4.46 | Nov 30
Innate Immune Function by Toll-Like Receptors: Distinct Responses in Newborns and the Elderly Kollmann, TR; Levy, O; Montgomery, RR; Goriely, S Immunity 2012-11-16 4.45 | Nov 23
Peripheral Tissue Surveillance and Residency by Memory T Cells Gebhardt, T; Mueller, SN; Heath, WR; Carbone, FR Trends Immunol 2012-10-02 4.38 | Oct 5
The Anatomical and Cellular Basis of Immune Surveillance in the Central Nervous System Ransohoff, RM; Engelhardt, B Nat Rev Immunol 2012-08-20 4.32 | Aug 24
FOXO Transcription Factors Throughout T Cell Biology Hedrick, SM; Hess Michelini, R; Doedens, AL; Goldrath, AW; Stone, EL Nat Rev Immunol 2012-09-01 4.32 | Aug 24
The Role of the T Follicular Helper Cells in Allergic Disease Kemeny, DM Cell Mol Immunol 2012-08-02 4.32 | Aug 24
Endogenous Modulators of Inflammatory Cell Recruitment Hajishengallis, G; Chavakis, T Trends Immunol 2012-08-30 4.33 | Aug 31
Capture, Crawl, Cross: The T Cell Code to Breach the Bloodbrain Barriers Engelhardt, B; Ransohoff, RM Trends Immunol 2012-08-25 4.33 | Aug 31
Consortium Biology in Immunology: the Perspective from the Immunological Genome Project Benoist, C; Lanier, L; Merad, M; Mathis, D Nat Rev Immunol 2012-09-07 4.34 | Sep 7
Unconventional Recognition of Peptides by T Cells and the Implications for Autoimmunity Mohan, JF; Unanue, ER Nat Rev Immunol 2012-09-07 4.34 | Sep 7
Cytokine-Induced Cytokine Production by Conventional and Innate Lymphoid Cells Guo, L; Junttila, IS; Paul, WE Trends Immunol 2012-09-05 4.34 | Sep 7
IL-17-Producing γδ T Cells and Innate Lymphoid Cells Sutton, CE; Mielke, LA; Mills, KH Eur J Immunol 2012-09-05 4.35 | Sep 14
Germinal Center Kinases in Immune Regulation Yin, H; Shi, Z; Jiao, S; Chen, C; Wang, W; Greene, MI; Zhou, Z Cell Mol Immunol 2012-09-10 4.35 | Sep 14
Metabolic Checkpoints in Activated T Cells Wang, R; Green, DR Nat Immunol 2012-09-18 4.36 | Sep 21
T Cells Out of Control-Impaired Immune Regulation in the Inflamed Joint Wehrens, EJ; Prakken, BJ; van Wijk, F Nat Rev Rheumatol 2013-01-01 4.36 | Sep 21
HEVs; Lymphatics and Homeostatic Immune Cell Trafficking in Lymph Nodes Girard, JP; Moussion, C; Förster, R Nat Rev Immunol 2012-09-28 4.37 | Sep 28
Basic Principles of Tumor-Associated Regulatory T Cell Biology Savage, PA; Malchow, S; Leventhal, DS Trends Immunol 2012-09-19 4.37 | Sep 28
B Cells and Antibodies in Multiple Sclerosis Pathogenesis and Therapy Krumbholz, M; Derfuss, T; Hohlfeld, R; Meinl, E Nat Rev Neurol 2012-10-09 4.39 | Oct 12
Transcriptional Control of Effector and Memory CD8+ T Cell Differentiation Cui, W; Kaech, SM Nat Rev Immunol 2012-10-19 4.40 | Oct 19
Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease Sonnenberg, GF; Artis, D Immunity 2012-10-19 4.40 | Oct 19
Harnessing the Power of the Immune System to Target Cancer Lizée, G; Overwijk, WW; Radvanyi, L; Gao, J; Sharma, P; Hwu, P Annu Rev Med 2012-10-22 4.41 | Oct 26
Defining the Nature of Human γδ T Cells: A Biographical Sketch of the Highly Empathetic Kalyan, S; Kabelitz, D Cell Mol Immunol 2012-10-22 4.41 | Oct 26
High Density Lipoprotein Biogenesis; Cholesterol Efflux; and Immune Cell Function Sorci-Thomas, MG; Thomas, MJ Arterioscler Thromb Vasc Biol 2012-11-01 4.42 | Nov 2
Guarding the Perimeter: Protection of the Mucosa by Tissue-Resident Memory T Cells Cauley, LS; Lefrançois, L Mucosal Immunol 2012-11-07 4.43 | Nov 9
Recognition of CD1d-Restricted Antigens by Natural Killer T Cells Rossjohn, J; Pellicci, DG; Patel, O; Gapin, L; Godfrey, DI Nat Rev Immunol 2012-11-16 4.44 | Nov 16